Cardno ChemRisk Proposition 65 Newsletter: April

Cardno ChemRisk offers scientific consulting services, specializing in using risk assessment methods to characterize and provide improved understanding of exposures involving chemicals in a range of products and scenarios. You can find a full list of our services and example projects on our Proposition 65 (Prop 65) qualification sheet.

Cardno ChemRisk Service Spotlight: Hemp-Derived Products & Ingredients Services

The use and availability of hemp-derived products and ingredients has increased following the Agricultural Improvement Act of 2018. Products containing hemp and/or hemp-derived ingredients range from personal care products such as lotions and lip balms to electronic vaping devices or pet treats and foods/beverages. However, as the regulatory landscape surrounding cannabis and hemp continues to evolve, there are considerable gaps in the safety and quality of these consumer products, which are often sold and marketed without proper oversight. Manufacturers and users of products containing hemp-derived ingredients need to understand the associated risks, as well as current state and future federal regulations. Cardno ChemRisk scientists offer consulting services for characterizing the potential exposures and health risks posed by various chemicals in consumer products, foods, and personal care products, using state-of-the-art risk assessment methods. Our team offers a multidisciplinary approach to resolving health and safety issues that may arise with consumer products or at the workplace, as well as providing support related to epidemiological and clinical studies. For inquires about our capabilities, please contact Elise de Gandiaga, Heidi O’Neill, or Kara Keeton.

PFAS Contamination in Seafood

Since 2019, the FDA has analyzed Total Diet Study (TDS) samples for 16 select per- and polyfluoroalkyl substances (PFAS) as a part of the efforts to monitor nutrients and contaminants in the U.S. food supply. Such samples have been utilized to determine potential human health concerns associated with the detectable levels of PFAS in foods and the likely human consumption patterns of these foods. In June of 2021, the FDA announced that it intended to conduct a targeted survey of PFAS in the most commonly consumed seafood in the U.S. Of the 440 samples analyzed, only seven food samples had detectable PFAS levels; five of these PFAS-containing samples were from processed seafood. While the FDA has indicated that efforts to monitor contaminants in the U.S. food supply are ongoing, the administration concluded that there is no indication of human health concern from PFAS in the U.S. food supply (FDA, 2021a; FDA, 2021b; FDA, 2021c). For more information about this topic, please read the blog An Overview of PFAS Contamination in Seafood. For inquiries about our capabilities with PFAS, please reach out to Heather Lynch.

New Bans for Art or Craft Materials in California for Kindergarten through 6th Grade Schools

Recently, the California Education Code has prohibited schools from purchasing art or craft materials that contain what they define as “toxic” substances intended for use by school children in grades Kindergarten to 6th (K-6). In addition, art materials sold in California must also comply with Proposition 65. As part of CA Education Code § 32064, OEHHA developed a full list of products that schools are prohibited from purchase by teachers with the intent for use by K-6 students. This list of prohibited art and crafts materials span a variety of product types including adhesives (i.e. glue, rubber cement, spray adhesives), brush care products (i.e. mineral spirits, turpentine), ceramics and sculpting materials (i.e. clay, plaster, glazes), cleaners, solvents, drawing and coloring supplies, and paints. These prohibited products all have specific ingredients and corresponding warning label statements that resulted in their placement on this list (Cal. Education Code § 32064; OEHHA, 2019; OEHHA, 2018; OEHHA, 2021). For more information about this topic, please read our blog. For inquiries about our capabilities in performing exposure and safety assessments for consumer products, please reach out to Dr. Annette Santamaria or Dr. Ernest Fung.

 Updates with PFOS and PFOA

During the OEHHA’s public workshop in September, Public Health Goals (PHGs) and Health Protective Concentrations (HPCs) were proposed for PFOA and PFOS in drinking water. While not enforceable, these values form the basis for derivation of enforceable drinking water standards. These PHGS and HPCs are among the most stringent state-level guidance values released to date for any PFAS; however, these values incorporate several uncertainty factors to account for data gaps, inter- and intraspecies differences, and other considerations, providing a substantial margin of safety. Additionally, in September OEHHA announced that the Carcinogen Identification Committee (CIC) plans to meet to discuss the possible listing of PFOS under Proposition 65 for cancer endpoints (OEHHA, 2021a; OEHHA, 2021b; OEHHA, 2021c; OEHHA, 2021d; OEHHA, 2021e). For more information regarding PFAS, please reach out to Heather Lynch.

Meet the author:


Kathy Chan



Please visit the Proposition 65 section of our website to learn more about our services!

For more information regarding Cardno ChemRisk’s Proposition 65 capabilities, please contact Ania Urban, PhD, MPH.