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Antimicrobial Agents: Safety and Other Considerations
in Selection and Use.
Antimicrobial agents (i.e., sanitizers, disinfectants, sterilants) are used to kill or inhibit the growth of harmful microbes. Products containing antimicrobial agents are routinely relied upon to ensure food and drug safety, prevent hospital-acquired infections, and treat drinking and wastewater, in addition to various other industrial, commercial, and residential applications. In the United States, antimicrobial agents are regulated primarily through the Environmental Protection Agency (EPA) and Food and Drug Administration based on their intended applications.
Project Example: EPA Re-Registration of Selected Antimicrobial Pesticides
Project Overview: Cardno ChemRisk was contacted to help assess toxicological and exposure data as part of efforts to re-register antimicrobial agents with EPA as antimicrobial pesticides (i.e., disinfectants).
Our Approach: As part of this project, we conducted several distinct tasks, including: 1) conducted systematic reviews of published data to characterize the critical effects and exposure-response relationships associated with exposures to selected antimicrobial agents; 2) developed exposure assessment strategies for healthcare and food processing facilities; and 3) prepared critiques of the EPA risk assessments for the selected antimicrobial agents.
Our Value: We were able to help our client by critically reviewing the evidence on the selected antimicrobial agents, preparing scientific assessments of workers’ potential exposures in various settings, and providing guidance on complex risk assessment issues.